CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 530 enrolled
Drug / intervention
NP101 - Sumatriptan iontophoretic transdermal patch +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00724815
NCT00724815Phase 3Completed

The Efficacy and Tolerability of NP101, a Sumatriptan Iontophoretic Transdermal Patch, in the Treatment of Acute Migraine: A Randomized, Double-Blind, Placebo-Controlled Study

NuPathe Inc.·interventional·Posted Jul 30, 2008·Updated Feb 4, 2016

In Brief

A Phase 3 clinical trial evaluating NP101 - Sumatriptan iontophoretic transdermal patch and Placebo for Migraine Disorders. Completed, enrolled 530 participants across 34 sites.

Detailed Summary

This study was a randomized, parallel group, double-blind, placebo controlled design to compare the efficacy and tolerability of NP101 to a placebo iontophoretic transdermal patch. The primary objective of this study was to assess the proportion of subjects who were headache pain free at two hours after patch activation. Key secondary objectives included: 1. The proportion of subjects who were nausea free at two hours after patch activation. 2. The proportion of subjects who were photophobia free at two hours after patch activation. 3. The proportion of subjects who were phonophobia free at two hours after patch activation.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 3CompletedFinished
2009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedJul 30, 2008
Enrollment StartJan 1, 2009
Primary CompletionJul 1, 2009
TodayJul 2, 2026
Enrollment to primary: 6 monthsPosted 17.9 years ago

Interventions

NP101 - Sumatriptan iontophoretic transdermal patchdrug

Sumatriptan iontophoretic transdermal patch

Placebodrug

NP101 Placebo iontophoretic transdermal patch