At a glance
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Prospective Study to Assess the Anatomical Relationship of Level IB Lymph Nodes to the Submandibular Gland in Patients With Carcinoma of the Upper Aerodigestive Tract
In Brief
A Phase 1 clinical trial evaluating neck dissection of at least the ipsilateral sub-level 1B for Carcinoma. Completed, enrolled 22 participants across 1 site.
Detailed Summary
Hypothesis 1. The submandibular gland is not a lymphatic organ and usually remains uninvolved with head and neck cancer despite the presence of metastatic disease in the lymph nodes that surround it. 2. All the lymph nodes in the submandibular triangle can be removed without resection of the submandibular gland. Study Design A better understanding of the frequency of submandibular gland involvement may lead to refined treatment strategies for head and neck cancer, which can possibly spare removal of the submandibular gland and potentially improve the long term side effects from therapy.
Study Details
Timeline
Interventions
neck dissection of at least the ipsilateral sub-level 1B