CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 92 enrolled
Drug / intervention
1) hyperventilation via noninvasive positive pressure ventilation 2) multiple trials of episodic hypoxiaother
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00732199
NCT00732199N/ACompleted
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Determinants of Age-specific Breathing Instability During Sleep

VA Office of Research and Development·interventional·Posted Aug 11, 2008·Updated Jun 28, 2017

In Brief

A clinical study evaluating 1) hyperventilation via noninvasive positive pressure ventilation 2) multiple trials of episodic hypoxia for Sleep Apnea and Age. Completed, enrolled 92 participants across 1 site.

Detailed Summary

The purpose for this research protocol was to examine the role of breathing control mechanisms that determine the development of sleep-disordered breathing in the elderly. This proposal focused on key factors that contribute to the control of ventilation in elderly adults during sleep. The investigators studied the age-specific changes in ventilatory control in older and young adults during NREM sleep.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsSleep Apnea, Age
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
2009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedAug 11, 2008
Enrollment StartOct 1, 2008
Primary CompletionApr 1, 2015
TodayJul 2, 2026
Enrollment to primary: 6.5 yearsPosted 17.9 years ago

Interventions

1) hyperventilation via noninvasive positive pressure ventilation 2) multiple trials of episodic hypoxiaother

1\) noninvasive hyperventilation to determine apneic threshold; 2) episodic hypoxia to determine ventilatory long term facilitation