CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 125 enrolled
Drug / intervention
Vitamin D3 +1 moredrug
Likely dose
Vitamin D3 4000 unitsfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00736632
NCT00736632N/ACompleted
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Vitamin D, Insulin Resistance, and Cardiovascular Disease

Washington University School of Medicine·interventional·Posted Aug 18, 2008·Updated Feb 10, 2020

In Brief

A clinical study evaluating Vitamin D3 and Placebo for Vitamin D Deficiency and 4 related conditions. Completed, enrolled 125 participants across 1 site.

Detailed Summary

In recent years, vitamin D has been shown not only to be important for bone and calcium metabolism but also for homeostasis of critical tissues involved in vascular disease in patients with diabetes. Epidemiological studies indicated the high prevalence of vitamin D deficiency among Type 2 DM patients and suggest an increased risk of cardiovascular disease and hypertension with low vitamin D levels. The objective of this proposal is to evaluate the effects of vitamin D replacement on blood pressure control and vascular disease in vitamin D deficient hypertensive patients with diabetes

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsVitamin D Deficiency, Insulin Resistance, Type 2 Diabetes Mellitus, Cardiovascular Disease, Hypertension
CountriesUnited States
CollaboratorsNational Heart, Lung, and Blood Institute (NHLBI), American Diabetes Association

Timeline

N/ACompletedFinished
2006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedAug 18, 2008
Enrollment StartMay 1, 2006
Primary CompletionJan 13, 2019
TodayJul 2, 2026
Enrollment to primary: 12.7 yearsPosted 17.9 years ago

Interventions

Vitamin D3drug

Cholecalciferol 4000 units orally daily Calcium carbonate 500 mg orally twice daily

Placebodrug

Placebo pill orally daily Calcium carbonate 500 mg twice daily