CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 260 enrolled
Drug / intervention
Nasal swab under endoscopic guidanceprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00739921
NCT00739921N/ACompleted
CompareCT.gov

PCR Analysis of Nasal Polyps for Fungal DNA

University of California, San Francisco·interventional·Posted Aug 22, 2008·Updated Dec 4, 2019

In Brief

A clinical study evaluating Nasal swab under endoscopic guidance for Sinusitis and Nasal Polyps. Completed, enrolled 260 participants across 1 site.

Detailed Summary

The objective of this study is to determine whether the amount or type of fungal DNA present in the nose and home environment can be correlated with the outcomes of the following quality of life (QOL) instruments: Medical Outcomes Study 36-item Short Form (SF-36) and the Sino-Nasal Outcomes Study - 20 Questions (SNOT-20).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsSinusitis, Nasal Polyps
CountriesUnited States
CollaboratorsEnvironmental Protection Agency (EPA)

Timeline

N/ACompletedFinished
2006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedAug 22, 2008
Enrollment StartJun 1, 2006
Primary CompletionMay 1, 2015
TodayJul 2, 2026
Enrollment to primary: 8.9 yearsPosted 17.9 years ago

Interventions

Nasal swab under endoscopic guidanceprocedure

After the application of pontocaine and neosynephrine spray, the following will be done: * A small sponge applicator will be used to swab the inside of your mouth for saliva collection * A blood sample (6cc - one tube) will be collected * A small brush applicator called a cytology brush and an instrument called an endoscope will be used to swab the inside of your nose (middle meatus) * Subjects will be asked to complete 2 standard quality of life questionnaires regarding how much your symptoms bother you * You will be asked to bring in a vacuum cleaner bag from home at a follow-up appointment which will be swabbed as well The samples will be refrigerated and analyzed using PCR to detect and speciate fungus.