CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 171 enrolled
Drug / intervention
Transcatheter Pulmonary Valve replacementdevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00740870
NCT00740870N/ACompleted

Implantation of the Medtronic Melody Transcatheter Pulmonary Valve in Patients With Dysfunctional Right Ventricular Outflow Tract (RVOT) Conduits: A Feasibility Study

Medtronic Cardiovascular·interventional·Posted Aug 25, 2008·Updated Mar 26, 2024

In Brief

A clinical study evaluating Transcatheter Pulmonary Valve replacement for Congenital Heart Defects and Dysfunctional Right Ventricular Outflow Tract Conduits. Completed, enrolled 171 participants across 5 sites.

Detailed Summary

The primary objective is to confirm the long-term functionality of implantation of the Medtronic Melody TPV at 5 years is no worse than the historical control established through literature review. The secondary objectives are to evaluate long-term functionality at 10 years and to assess safety, procedural success, and clinical utility of transcatheter implantation of the Melody TPV.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedAug 25, 2008
Enrollment StartJan 1, 2007
Primary CompletionMay 1, 2015
Study CompletionAug 21, 2020
TodayJul 2, 2026
Enrollment to primary: 8.3 yearsPosted 17.9 years ago

Interventions

Transcatheter Pulmonary Valve replacementdevice

Transcatheter valve implantation into a RVOT conduit in patients with complex congenital heart defects where the conduit has become dysfunctional and where the patient needs invasive intervention.