CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 120 enrolled
Drug / intervention
MaZiRenWan (MZRW) +1 moredrug
Likely dose
MaZiRenWan (MZRW) 150mlfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00741936
NCT00741936Phase 2Completed
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Chinese Herbal Medicine for Functional Constipation: A Randomized, Double-blind, Placebo Controlled Trial

Hong Kong Baptist University·interventional·Posted Aug 26, 2008·Updated Jun 24, 2016

In Brief

A Phase 2 clinical trial evaluating MaZiRenWan (MZRW) and Placebo for Functional Gastrointestinal Disorders and Constipation. Completed, enrolled 120 participants across 1 site.

Detailed Summary

Functional constipation (FC) is a common complaint in clinical practice, but treatment for this condition in conventional medicine is suboptimal. Complementary and alternative medicines, especially Chinese herbal medicine (CHM) are used frequently by patients, however, there is little research evidence about these commonly used CHM. The purpose of the study is evaluate the efficacy and safety of an ancient CHM formula, MaZiRenWan (MZRW), by comparing with placebo.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsFunctional Gastrointestinal Disorders, Constipation
CountriesChina
CollaboratorsFood and Health Bureau, Hong Kong, Purapharm International (Hk) Ltd.

Timeline

Phase 2CompletedFinished
20082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedAug 26, 2008
Enrollment StartJul 1, 2008
Primary CompletionNov 1, 2009
Study CompletionDec 1, 2009
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 17.8 years ago

Interventions

MaZiRenWan (MZRW)drug

MZRW granule dissolved in 150ml hot water (oral), 7.5g/sachet, twice daily

Placebodrug

Placebo granule dissolved in 150ml hot water (oral), 7.5g/sachet, twice daily