CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 45 enrolled
Drug / intervention
Prednisone 15 mg +3 moredrug
Likely dose
Prednisone 15 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00746512
NCT00746512Phase 1Completed

A Randomized, Double-Blind, Parallel Group, Placebo Controlled Study to Access the Effects of Oral Prednisone on Clinical Efficacy and the Power Doppler Ultrasound Signal of Synovium in Patients With Rheumatoid Arthritis

Merck Sharp & Dohme LLC·interventional·Posted Sep 4, 2008·Updated May 29, 2015

In Brief

A Phase 1 clinical trial evaluating Prednisone 15 mg, Placebo Tablets, and 2 other interventions for Rheumatoid Arthritis. Completed, enrolled 45 participants.

Detailed Summary

The study will compare the effects of prednisone vs placebo on synovial blood flow and overall DAS (disease activity score) in patients with rheumatoid arthritis.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
Countries--
Collaborators--

Timeline

Phase 1CompletedFinished
200920102011201220132014201520162017201820192020202120222023202420252026
First PostedSep 4, 2008
Enrollment StartSep 1, 2008
Primary CompletionSep 1, 2009
TodayJul 2, 2026
Enrollment to primary: 1 yearPosted 17.8 years ago

Interventions

Prednisone 15 mgdrug

Prednisone 15 mg tablets once daily for 15 days.

Placebo Tabletsdrug

Prednisone placebo tablets once daily for 15 days.

Prednisone 7.5 mgdrug

Prednisone 7.5 mg over-encapsulated tablets once daily for 15 days

Placebo Over-Encapsulated Tabletsdrug

Prednisone 7.5 mg placebo over-encapsulated tablets once daily for 15 days