CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 24 enrolled
Drug / intervention
Lisdexamfetamine Dimesylate +1 moredrug
Likely dose
Lisdexamfetamine Dimesylate 50mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00746733
NCT00746733Phase 1Completed

A Phase I, Open-Label, Randomized, Four Period Crossover Drug Interaction Study to Evaluate the Pharmacokinetic Profiles of VYVANSE™ and ADDERALL XR When Each is Administered Alone and in Combination With the Proton Pump Inhibitor Prilosec OTC™ in Healthy Adult Volunteers

Shire·interventional·Posted Sep 4, 2008·Updated Jun 14, 2021

In Brief

A Phase 1 clinical trial evaluating Lisdexamfetamine Dimesylate and Adderall XR (mixed salts amphetamine) for Healthy Volunteers. Completed, enrolled 24 participants across 1 site.

Detailed Summary

The purpose of this study is to determine if taking Vyvanse with Prilosec OTC or Adderall XR with Prilosec OTC changes how quickly the drug is absorbed into the body and/or changes how much of the drug is absorbed into the body.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 1CompletedFinished
200920102011201220132014201520162017201820192020202120222023202420252026
First PostedSep 4, 2008
Enrollment StartSep 8, 2008
Primary CompletionOct 26, 2008
TodayJul 2, 2026
Enrollment to primary: 2 monthsPosted 17.8 years ago

Interventions

Lisdexamfetamine Dimesylatedrug

50mg capsule

Adderall XR (mixed salts amphetamine)drug

20mg capsule