At a glance
ClinicalIndex Comparison RecordN/ACompleted· 99 enrolled
Drug / intervention
Lexaprodrug
Likely dose
Lexapro 10 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
fMRI Studies of Emotional Circuitry in Major Depression
In Brief
A clinical study evaluating Lexapro for Depression. Completed, enrolled 99 participants.
Detailed Summary
This study will examine activation of a brain circuit that regulates emotion in depressed patients before and after treatment to see which areas of the brain are involved in chronic depression.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsDepression
Countries--
CollaboratorsNational Institute of Mental Health (NIMH)
Timeline
N/ACompletedFinished
200120022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
Enrollment StartJul 2001
Primary CompletionJan 2008
Study CompletionJun 2008
First PostedSep 2008
TodayJul 2026
First PostedSep 9, 2008
Enrollment StartJul 1, 2001
Primary CompletionJan 1, 2008
Study CompletionJun 1, 2008
TodayJul 2, 2026
Enrollment to primary: 6.5 yearsPosted 17.8 years ago
Interventions
Lexaprodrug
10 mg by mouth once per day for first 2 weeks, with psychiatric re-evaluation every 2 weeks to determine if any change in dosage is required, with a maximum of 20 mg per day