At a glance
ClinicalIndex Comparison RecordPhase 4Completed· 76 enrolled
Drug / intervention
Valve surgery with removal of vegetationsprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Randomized Comparison of Early Surgery Versus Conventional Treatment Strategy in Patients With High Embolic Risk of Infective Endocarditis
In Brief
A Phase 4 clinical trial evaluating Valve surgery with removal of vegetations for Endocarditis. Completed, enrolled 76 participants across 2 sites.
Detailed Summary
There have been no prospective clinical studies in infective endocarditis comparing early surgery with the conventional treatment strategy based on current guidelines. The purpose of this prospective randomized trial is to compare clinical outcomes of early surgery versus conventional treatment strategy in patients with high embolic risk of infective endocarditis.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsEndocarditis
CountriesSouth Korea
Collaborators--
Timeline
Phase 4CompletedFinished
200720082009201020112012201320142015201620172018201920202021202220232024202520262027
Enrollment StartSep 2006
First PostedSep 2008
Primary CompletionApr 2011
Study CompletionSep 2011
TodayJul 2026
First PostedSep 10, 2008
Enrollment StartSep 1, 2006
Primary CompletionApr 1, 2011
Study CompletionSep 1, 2011
TodayJul 2, 2026
Enrollment to primary: 4.6 yearsPosted 17.8 years ago
Interventions
Valve surgery with removal of vegetationsprocedure
Early valve repair or replacement with removal of vegetations within 48 hours of randomization