At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Randomized,Double-Blind,Placebo-Controled Trial of Selective Digestive Decontamination Using Oral Gentamicin and Oral Polymyxin E for Eradication of Carbapenem-Resistant Klebsiella Pneumoniae Carriage
In Brief
A clinical study evaluating Arm #1 :Oral solution and buccal gel of gentamicin and polymyxin E. Arm #2: Placebo. for Carriage of Carbapemen-resistant Klebsialle Pneumoniae. Completed, across 1 site.
Detailed Summary
There is an urgent need to control our current national outbreak of carbapenem-resistant Klebsiella pneumoniae (CRKP). The purpose of this study is to eradicate CRKP gastrointestinal carriage using selective digestive decontamination (SDD); with buccal and oral gentamicin and polymyxin E administration. This will reduce infections and hopefully mortality caused by CRKP.
Study Details
Timeline
Interventions
Arm #1: Oral gentamicin \& polymyxin E, gentamicin \& polymyxin E buccal gel. Arm #2: Oral placebo solutions, placebo buccal gel.