CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 447 enrolled
Drug / intervention
Surgical mask +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00756574
NCT00756574N/ACompleted

A Randomized Control Trial of Surgical Masks vs N95 Respirators to Prevent Influenza in Health Care Workers

McMaster University·interventional·Posted Sep 22, 2008·Updated Oct 29, 2018

In Brief

A clinical study evaluating Surgical mask and N95 mask for Influenza. Completed, enrolled 447 participants across 1 site.

Detailed Summary

The goal of this study is to compare the efficacy of the surgical mask to the N95 respirator in protecting nurses from influenza in the hospital setting. The investigators propose a non-inferiority randomized controlled trial whereby nurses are randomized to either a surgical mask or an N95 respirator when caring for patients with febrile respiratory illness during the influenza season. The hypothesis is that the surgical mask offers similar protection against influenza to that of the N95. The specific objective of the study is to assess whether the rates of influenza (laboratory-confirmed by PCR and HAI assay), as well as secondary outcomes (influenza-like illness, work-related absenteeism, physician visits for respiratory illness, and lower respiratory infection), are similar among nurses using a surgical mask compared to those using an N95 respirator.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsInfluenza
CountriesCanada
CollaboratorsHealth Canada

Timeline

N/ACompletedFinished
200920102011201220132014201520162017201820192020202120222023202420252026
First PostedSep 22, 2008
Enrollment StartOct 1, 2008
Primary CompletionApr 1, 2009
Study CompletionMay 1, 2009
TodayJul 2, 2026
Enrollment to primary: 6 monthsPosted 17.8 years ago

Interventions

Surgical maskdevice

Surgical mask worn for patients with febrile respiratory illness

N95 maskdevice

N95 mask worn for patients with febrile respiratory illness