At a glance
ClinicalIndex Comparison RecordPhase 2Completed· 79 enrolled
Drug / intervention
D-Cycloserine (DCS) +1 moredrug
Likely dose
D-Cycloserine (DCS) 50 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
D-Cycloserine Facilitation of Cocaine - Cue Extinction
In Brief
A Phase 2 clinical trial evaluating D-Cycloserine (DCS) and Placebo for Cocaine Use Disorders. Completed, enrolled 79 participants across 2 sites.
Detailed Summary
The purpose of this study is to explore the use of d-cycloserine (DCS) to facilitate extinction of response to cocaine cues in cocaine-dependent individuals, in hopes that it may lead to the development of new treatment options for cocaine dependence.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCocaine Use Disorders
CountriesUnited States
CollaboratorsNational Institute on Drug Abuse (NIDA)
Timeline
Phase 2CompletedFinished
200920102011201220132014201520162017201820192020202120222023202420252026
Enrollment StartSep 2008
First PostedSep 2008
Primary CompletionOct 2011
TodayJul 2026
First PostedSep 25, 2008
Enrollment StartSep 1, 2008
Primary CompletionOct 1, 2011
TodayJul 2, 2026
Enrollment to primary: 3.1 yearsPosted 17.8 years ago
Interventions
D-Cycloserine (DCS)drug
50 mg d-cycloserine or placebo taken orally
Placebodrug