CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 34 enrolled
Drug / intervention
Vytorin +1 moredrug
Likely dose
Simvastatin 20 milligramsfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00762164
NCT00762164Phase 4Completed
CompareCT.gov

Comparative Efficacy of a Vytorin 10/80 Tablet Split Into 4 (Estimated Dose Ezetimibe 2.5 + Simvastatin 20) Versus Simvastatin 20 Milligrams on LDL Cholesterol

Bronx VA Medical Center·interventional·Posted Sep 30, 2008·Updated Jul 3, 2013

In Brief

A Phase 4 clinical trial evaluating Vytorin and Simvastatin for Hypercholesterolemia. Completed, enrolled 34 participants across 1 site.

Detailed Summary

The purpose of this study is to compare the efficacy of a Vytorin 10/80 tablet, an approved agent for the treatment of elevated LDL cholesterol which combines the cholesterol absorption inhibitor Ezetimibe 10 mg and simvastatin 80 mg, when split into 4 using a tablet splitter, versus a whole simvastatin 20 milligram tablet.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHypercholesterolemia
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedSep 30, 2008
Enrollment StartMar 1, 2007
Primary CompletionApr 1, 2009
Study CompletionMay 1, 2009
TodayJul 2, 2026
Enrollment to primary: 2.1 yearsPosted 17.8 years ago

Interventions

Vytorindrug

Vytorin 10/80 split into 4

Simvastatindrug

Simvastatin 20 milligrams