At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
2B or Not 2B? Shoulder Function After Level 2B Neck Dissection: A Randomized Controlled
In Brief
A clinical study evaluating Selective Neck Dissection Excluding Level 2B and Selective Neck Dissection Including Level 2B for Head and Neck Squamous Cell Carcinoma. Completed, enrolled 40 participants across 1 site.
Detailed Summary
Many types of head and neck cancers will have local spread to the neck. As such selective neck dissection is performed as part of the treatment. The neck is divided into various levels. Selective neck dissection targets areas that are most likely to harbor cancer cells for specific types of head and neck cancers. Level IIB has been particularly controversial in the last few years, as the rate of cancer spread to this area has been shown to be quite low (0-8%). Moreover, because the spinal accessory nerve (involved in shoulder function) runs through this area, there is theoretical risk of causing post-operative shoulder weakness. As such, the question of whether removing level IIB, knowing that there is low chance of it containing disease spread, is worth risking decreased shoulder function. Some would argue that all potential diseased sites should be removed at all costs. While other advocate that a balance between disease cure and function should be maintained. However, what needs to be determined is just what impact does dissecting IIB have on shoulder function. At our institution, the rate of poor shoulder function associated with selective neck dissection has been perceived as being quite low. This study is designed to test this observation. Hypothesis: Neck dissection including level IIb in head and neck cancer patients will not lead to worse shoulder function and quality of life than when level IIb is preserved.
Study Details
Timeline
Interventions
Selective neck dissection is performed. Level 2a is dissected; level 2b is not dissected.
Selective neck dissection is performed. Level 2a is dissected; level 2b is also dissected.