At a glance
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Low Vision Depression Prevention Trial for Age Related Macular Degeneration
In Brief
A Phase 3 clinical trial evaluating BA-LVR and ST-LVR for Age-related Macular Degeneration and Depression. Completed, enrolled 188 participants across 1 site.
Detailed Summary
This randomized, controlled clinical trial, the Low Vision Depression Prevention TriAL (VITAL), will test the efficacy of collaborative low vision rehabilitation (LVR) to prevent depressive disorders in Age-Related Macular Degeneration (AMD). In this innovative intervention, a low vision occupational therapist collaborates with a low vision optometrist to develop and implement a care plan based on a subject's vision status, rehabilitation potential, and personal rehabilitation goals. An independent rater masked to treatment assignment will assess depressive disorders meeting DSM-IV criteria (primary outcome) and targeted vision function and vision-related quality of life (secondary outcomes) at baseline and then at 4 months to evaluate short-term effects (main trial end point) and at 12 months to evaluate long-term effects.
Study Details
Timeline
Interventions
Low vision clinic-based optometry plus 6 in-home occupational therapy visits
Clinic-based low vision optometry plus 6 in-home sessions of Supportive Therapy