CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 141 enrolled
Drug / intervention
Ketotifen/naphazoline +3 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00770133
NCT00770133Phase 3Completed

A Multi-center, Double-masked, Randomized, Placebo-controlled Evaluation of the Onset and Duration of Action of KetoNaph Ophthalmic Solution in the Conjunctival Allergen Challenge (CAC) Model of Acute Allergic Conjunctivitis.

Bausch & Lomb Incorporated·interventional·Posted Oct 9, 2008·Updated Oct 27, 2020

In Brief

A Phase 3 clinical trial evaluating Ketotifen/naphazoline, Naphazoline, and 2 other interventions for Allergic Conjunctivitis. Completed, enrolled 141 participants across 1 site.

Detailed Summary

The purpose of this study is to establish the safety and efficacy of ketotifen/naphazoline ophthalmic solution compared to vehicle and its individual components in alleviating the signs and symptoms of conjunctival allergen challenge (CAC)-induced allergic conjunctivitis.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States
Collaborators--

Timeline

Phase 3CompletedFinished
200920102011201220132014201520162017201820192020202120222023202420252026
First PostedOct 9, 2008
Enrollment StartFeb 1, 2010
Primary CompletionApr 1, 2010
Study CompletionJun 1, 2010
TodayJul 2, 2026
Enrollment to primary: 2 monthsPosted 17.7 years ago

Interventions

Ketotifen/naphazolinedrug

One drop of ketotifen fumarate 0.025% and naphazoline HCl 0.05% ophthalmic solution at visit 3 and visit 4.

Naphazolinedrug

One drop of naphazoline HCl 0.05% ophthalmic solution at visits 3 and 4.

Ketotifendrug

One drop of ketotifen fumarate 0.025% ophthalmic solution at visits 3 and 4.

Vehicledrug

One drop of vehicle ophthalmic solution at visit 3 and visit 4.