At a glance
ClinicalIndex Comparison RecordN/ACompleted· 168 enrolled
Drug / intervention
Amantadine Hydrochloride +1 moredrug
Likely dose
Amantadine Hydrochloride 100 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Multi-Center, Parallel-Group, Randomized, Double-Blind, Placebo-Controlled Trial of Amantadine Hydrochloride in the Treatment of Chronic Traumatic Brain Injury Irritability and Aggression: A Replication Study
In Brief
A clinical study evaluating Amantadine Hydrochloride and Placebo for Brain Injury and Aggression. Completed, enrolled 168 participants across 6 sites.
Detailed Summary
The purpose of this study is to study the effect of amantadine on irritability and aggression caused by traumatic brain injury.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsBrain Injury, Aggression
CountriesUnited States
Timeline
N/ACompletedFinished
200920102011201220132014201520162017201820192020202120222023202420252026
First PostedOct 2008
Enrollment StartAug 2009
Primary CompletionApr 2013
Study CompletionMay 2013
TodayJul 2026
First PostedOct 24, 2008
Enrollment StartAug 1, 2009
Primary CompletionApr 1, 2013
Study CompletionMay 1, 2013
TodayJul 2, 2026
Enrollment to primary: 3.7 yearsPosted 17.7 years ago
Interventions
Amantadine Hydrochloridedrug
100 mg every morning and noon
Placebodrug
one placebo tablet every morning and 12 Noon