At a glance
ClinicalIndex Comparison RecordPhase 1Completed· 200 enrolled
Drug / intervention
Neostigmine +2 moredrug
Likely dose
fentanyl 2 mcgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Epidural Neostigmine Dose Response for the Treatment of Labor Pain
In Brief
A Phase 1 clinical trial evaluating Neostigmine, Bupivacaine, and 1 other intervention for Labor Pain. Completed, enrolled 200 participants across 1 site.
Detailed Summary
The purpose of this study is to see which dose of epidural neostigmine is the best additive to use with the numbing medication used in an epidural during labor.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsLabor Pain
CountriesUnited States
Collaborators--
Timeline
Phase 1CompletedFinished
200920102011201220132014201520162017201820192020202120222023202420252026
Enrollment StartOct 2008
First PostedOct 2008
Primary CompletionNov 2013
TodayJul 2026
First PostedOct 24, 2008
Enrollment StartOct 1, 2008
Primary CompletionNov 1, 2013
TodayJul 2, 2026
Enrollment to primary: 5.1 yearsPosted 17.7 years ago
Interventions
Neostigminedrug
utilizing 3 different dosages of neostigmine and comparing it to the standard of fentanyl. Infusion runs via PCA throughout labor analgesia.
Bupivacainedrug
fentanyldrug
fentanyl 2 mcg/ml