CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 27 enrolled
Drug / intervention
D-cycloserine +1 moredrug
Likely dose
D-cycloserine 50 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00780442
NCT00780442Phase 2Completed
CompareCT.gov

D-Cycloserine and Cue Exposure in Cocaine-Dependent Individuals

Medical University of South Carolina·interventional·Posted Oct 27, 2008·Updated Jul 6, 2018

In Brief

A Phase 2 clinical trial evaluating D-cycloserine and Placebo for Cocaine Use Disorders. Completed, enrolled 27 participants across 1 site.

Detailed Summary

In summary, this pilot study will explore the use of an innovative pharmacologic approach to the treatment of substance dependence through the facilitation of extinction of response to cocaine-conditioned cues in cocaine-dependent individuals. If DCS proves successful in this preliminary study, a controlled treatment trial will be planned. This novel approach could have implications for the treatment of multiple substance use disorders including methamphetamine, marijuana and opiate dependence.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsCocaine Use Disorders
CountriesUnited States
Collaborators--

Timeline

Phase 2CompletedFinished
200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedOct 27, 2008
Enrollment StartSep 1, 2006
Primary CompletionJul 1, 2008
TodayJul 2, 2026
Enrollment to primary: 1.8 yearsPosted 17.7 years ago

Interventions

D-cycloserinedrug

50 mg DCS

Placebodrug

Placebo