CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 177 enrolled
Drug / intervention
Panitumumab +3 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00788957
NCT00788957Phase 2Completed

A Randomized, Phase 1b/2 Trial of AMG 102 or AMG 479 in Combination With Panitumumab Versus Panitumumab Alone in Subject With Wild-Type KRAS Metastatic Colorectal Cancer

NantBioScience, Inc.·interventional·Posted Nov 11, 2008·Updated Aug 7, 2024

In Brief

A Phase 2 clinical trial evaluating Panitumumab, Ganitumab, and 2 other interventions for Colon Cancer and 4 related conditions. Completed, enrolled 177 participants.

Detailed Summary

This study is a global, multicenter, open-label phase 1b and randomized, double-blinded, 2 part, phase 2 study designed to evaluate the safety and efficacy of rilotumumab or ganitumab in combination with panitumumab versus panitumumab alone in patients with metastatic colorectal cancer whose tumors are wild-type KRAS status.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
Countries--
Collaborators--

Timeline

Phase 2CompletedFinished
200920102011201220132014201520162017201820192020202120222023202420252026
First PostedNov 11, 2008
Enrollment StartOct 27, 2008
Primary CompletionJul 23, 2010
TodayJul 2, 2026
Enrollment to primary: 1.7 yearsPosted 17.6 years ago

Interventions

Panitumumabdrug

Panitumumab for intravenous infusion

Ganitumabdrug

Ganitumab for intravenous infusion

Rilotumumabdrug

Rilotumumab for intravenous infusion

Placebodrug

Placebo intravenous infusion