CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 276 enrolled
Drug / intervention
Amoxicillin/Clavulanic Aciddrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00801099
NCT00801099N/ACompleted
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Benefit of a Single Preoperative Dose of Antibiotics in a Sub-Saharan District Hospital: Minimal Input, Massive Impact

Swiss Tropical & Public Health Institute·interventional·Posted Dec 3, 2008·Updated Aug 7, 2015

In Brief

A clinical study evaluating Amoxicillin/Clavulanic Acid for Surgical Site Infection. Completed, enrolled 276 participants across 1 site.

Detailed Summary

In a rural hospital in Tanzania the rate of surgical site infections (SSI) was 21.6%. Inappropriate choice of antibiotics and of administration time were determined as sole risk factors in this setting. After implementation of a standardized procedure with a single shot dose of Amoxicillin/Clavulanic Acid approximately 30 min. preoperatively the rate of SSI dropped by 80% in spite of procedural risk factors like poor hygiene etc.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsSurgical Site Infection
CountriesSwitzerland
CollaboratorsSwiss Academy of Medical Sciences (SAMS)

Timeline

N/ACompletedFinished
20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedDec 3, 2008
Enrollment StartDec 1, 2004
Primary CompletionMar 1, 2005
TodayJul 2, 2026
Enrollment to primary: 3 monthsPosted 17.6 years ago

Interventions

Amoxicillin/Clavulanic Aciddrug

single shot dose of Amoxicillin/Clavulanic Acid approximately 30 min. preoperatively