At a glance
ClinicalIndex Comparison RecordPhase 4Completed· 31 enrolled
Drug / intervention
doxycycline +1 moredrug
Likely dose
doxycycline 100mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Lipids of the Human Tear Film and Their Effect on Tear Stability
In Brief
A Phase 4 clinical trial evaluating doxycycline and azithromycin for Blepharitis. Completed, enrolled 31 participants across 1 site.
Detailed Summary
This prospective, randomized, comparative clinical trial evaluates the effect of either oral doxycycline, oral essential fatty acid, or topical azithromycin to modify the secretions of the meibomian gland in subjects with meibomian gland dysfunction and/or dry eye disease.
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsBlepharitis
CountriesUnited States
Collaborators--
Timeline
Phase 4CompletedFinished
20082009201020112012201320142015201620172018201920202021202220232024202520262027
Enrollment StartJul 2008
First PostedDec 2008
Primary CompletionDec 2010
TodayJul 2026
First PostedDec 5, 2008
Enrollment StartJul 1, 2008
Primary CompletionDec 1, 2010
TodayJul 2, 2026
Enrollment to primary: 2.4 yearsPosted 17.6 years ago
Interventions
doxycyclinedrug
Oral doxycycline 100mg bid
azithromycindrug
topical 1% azithromycin daily to eye