CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 24 enrolled
Drug / intervention
Placebo Oral Tablet +1 moredrug
Likely dose
Naltrexone 50 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00817089
NCT00817089Phase 4Completed

Defining an Endopheneotype for Alcohol Treatment With Naltrexone

University of Pennsylvania·interventional·Posted Jan 6, 2009·Updated Nov 21, 2019

In Brief

A Phase 4 clinical trial evaluating Placebo Oral Tablet and Naltrexone for Alcoholism. Completed, enrolled 24 participants across 1 site.

Detailed Summary

This is a study involving treatment for alcohol dependence among males of European or Asian decent. The ultimate aim of this line of investigation is to further establish a genetic link between alcohol dependence and treatment by defining an endophenotype associated with treatment response. The study consists of two inpatient alcohol challenge sessions with treatment using random assignment to either naltrexone or placebo.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAlcoholism
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
20082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedJan 6, 2009
Enrollment StartDec 1, 2007
Primary CompletionApr 1, 2010
Study CompletionJun 1, 2010
TodayJul 2, 2026
Enrollment to primary: 2.3 yearsPosted 17.5 years ago

Interventions

Placebo Oral Tabletdrug

Placebo pill

Naltrexonedrug

50 mg of naltrexone prior to challenge session