CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 32 enrolled
Drug / intervention
Clopidogrel 75 mg/day +2 moredrug
Likely dose
Clopidogrel 75 mg/dayfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00817999
NCT00817999Phase 4Completed
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The Impact of Grapefruit Juice on the Response to a Loading Dose and Maintenance Dose of Clopidogrel in Healthy Volunteers

Creighton University·interventional·Posted Jan 7, 2009·Updated Oct 1, 2012

In Brief

A Phase 4 clinical trial evaluating Grapefruit juice, Clopidogrel 75 mg/day, and 1 other intervention for Healthy. Completed, enrolled 32 participants across 1 site.

Detailed Summary

This study will measure the percentage of platelet aggregation inhibition with a loading dose of clopidogrel (300 mg) using the VerifyNow Assay System in healthy volunteers who have drank 11 oz of grapefruit juice. It will also measure the percentage of platelet aggregation inhibition with a maintenance dose of clopidogrel (75 mg/day) using the VerifyNow Assay System in healthy volunteers who have drank 11 oz grapefruit juice daily.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHealthy
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
200920102011201220132014201520162017201820192020202120222023202420252026
First PostedJan 7, 2009
Enrollment StartNov 1, 2008
Primary CompletionJul 1, 2011
TodayJul 2, 2026
Enrollment to primary: 2.7 yearsPosted 17.5 years ago

Interventions

Grapefruit juicedietary

Participants received grapefruit juice during 1 of the 2 periods.

Clopidogrel 75 mg/daydrug

Clopidogrel 300 mgdrug