CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 371 enrolled
Drug / intervention
bleomycin sulfate +11 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00822120
NCT00822120Phase 2Completed

A Phase II Trial of Response-Adapted Therapy of Stage III-IV Hodgkin Lymphoma Using Early Interim FDG-PET Imaging

SWOG Cancer Research Network·interventional·Posted Jan 14, 2009·Updated Aug 18, 2022

In Brief

A Phase 2 clinical trial evaluating bleomycin sulfate, filgrastim, and 10 other interventions for Lymphoma and Nonneoplastic Condition. Completed, enrolled 371 participants across 423 sites.

Detailed Summary

RATIONALE: Drugs used in chemotherapy work in different ways to stop the growth of cancer cells, either by killing the cells or by stopping them from dividing. Giving more than one drug (combination chemotherapy) may kill more cancer cells. G-CSF may help lessen the side effects in patients receiving chemotherapy. Imaging procedures, such as fludeoxyglucose F 18-PET/CT imaging, may help doctors predict how patients will respond to treatment. PURPOSE: This phase II trial is studying fludeoxyglucose F 18-PET/CT imaging to see how well it works in assessing response to combination chemotherapy and allow doctors to plan better additional further treatment in treating patients with stage III or stage IV Hodgkin lymphoma.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

Phase 2CompletedFinished
200920102011201220132014201520162017201820192020202120222023202420252026
First PostedJan 14, 2009
Enrollment StartJul 1, 2009
Primary CompletionApr 30, 2016
Study CompletionJun 30, 2022
TodayJul 2, 2026
Enrollment to primary: 6.8 yearsPosted 17.5 years ago

Interventions

bleomycin sulfatebiological

filgrastimbiological

ABVD regimendrug

BEACOPP regimendrug

cyclophosphamidedrug

dacarbazinedrug

doxorubicin hydrochloridedrug

etoposidedrug

prednisonedrug

procarbazine hydrochloridedrug

vinblastine sulfatedrug

vincristine sulfatedrug