At a glance
ClinicalIndex Comparison RecordPhase 3Completed· 825 enrolled
Drug / intervention
Abbreviated Zagreb 2-1-1 schedule +1 morebiological
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Phase III, Single Center, Randomized, Open-label Study, Comparing PCECV Administered in the Abbreviated Zagreb Regimen (2-1-1) to the Conventional Essen Regimen (1-1-1-1-1) in Healthy Volunteers in China
In Brief
A Phase 3 clinical trial evaluating Abbreviated Zagreb 2-1-1 schedule and Standard Essen 1-1-1-1-1 schedule for Rabies. Completed, enrolled 825 participants across 1 site.
Detailed Summary
This study investigates the safety and immunogenicity (non-inferiority) of a Purified Chick Embryo Cell Vaccine (PCECV) administered in two different schedules (conventional versus abbreviated schedule) in healthy adults 18 to 50 years of age in China
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsRabies
CountriesChina
Collaborators--
Timeline
Phase 3CompletedFinished
200920102011201220132014201520162017201820192020202120222023202420252026
Enrollment StartNov 2008
Primary CompletionDec 2008
Study CompletionJan 2009
First PostedJan 2009
TodayJul 2026
First PostedJan 21, 2009
Enrollment StartNov 1, 2008
Primary CompletionDec 1, 2008
Study CompletionJan 1, 2009
TodayJul 2, 2026
Enrollment to primary: 1 monthPosted 17.4 years ago
Interventions
Abbreviated Zagreb 2-1-1 schedulebiological
Subjects received the abbreviated Zagreb 2-1-1 schedule in a safety-lead-in phase.
Standard Essen 1-1-1-1-1 schedulebiological
Subjects received the standard Essen regimen.