At a glance
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Strength Training for Skeletal Muscle Adaptation After Stroke
In Brief
A clinical study evaluating Exercise- Strength Training and Exercise- Stretching Control for Stroke. Completed, enrolled 38 participants across 1 site.
Detailed Summary
Chronically disabled stroke survivors experience accelerated skeletal muscle atrophy and other detrimental changes to muscle and surrounding tissues on the paretic side. This unilateral tissue-level damage contributes to worsening disability and insulin resistance. This VA Merit Award will advance the investigators' understanding of the potential for strength training (ST) to reverse stroke-related muscle abnormalities to improve metabolic health, strength, and function. It will be the first study to thoroughly investigate the effects of ST on muscle atrophy, intramuscular fat, muscle fiber characteristics, capillary density and insulin sensitivity after stroke.
Study Details
Timeline
Interventions
3x per week lower-extremity ST lasting approximately 45 minutes to 1 hour.
3x per week upper and lower body stretching mixed with active and passive range of motion exercises