CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 79 enrolled
Drug / intervention
Ketamine +1 moredrug
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00833755
NCT00833755N/ACompleted
CompareCT.gov

Effect of Ketamine on Opioid-Induced Hyperalgesia

Massachusetts General Hospital·interventional·Posted Feb 2, 2009·Updated Jul 23, 2020

In Brief

A clinical study evaluating Ketamine and Placebos for Pain and 2 related conditions. Completed, enrolled 79 participants across 1 site.

Detailed Summary

The purpose of this study is to compare pain threshold, pain tolerance, and wind up, as measured by QST, before and after a single dose of ketamine infusion under two clinical conditions: chronic pain patients on opioid therapy and chronic pain patients without opioid therapy.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPain, Chronic Pain, Hyperalgesia
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
200920102011201220132014201520162017201820192020202120222023202420252026
First PostedFeb 2, 2009
Enrollment StartSep 1, 2008
Primary CompletionMay 1, 2013
Study CompletionApr 1, 2016
TodayJul 2, 2026
Enrollment to primary: 4.7 yearsPosted 17.4 years ago

Interventions

Ketaminedrug

To compare pain threshold, pain tolerance, and wind up, as measured by QST, before and after a single dose of ketamine infusion under two clinical conditions: chronic pain patients on opioid therapy and chronic pain patients without opioid therapy.

Placebosdrug

To compare pain threshold, pain tolerance, and wind up, as measured by QST, before and after a single dose of ketamine infusion under two clinical conditions: chronic pain patients on opioid therapy and chronic pain patients without opioid therapy.