At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Phase 1, Randomized, Patient And Investigator-blind, Placebo-controlled Study To Investigate The Safety, Tolerability, Pharmacokinetics And Pharmacodynamics Of Multiple Intravenously Administered Doses Of Pf-04236921 In Patients With Rheumatoid Arthritis Receiving Methotrexate
In Brief
A Phase 1 clinical trial evaluating Placebo, dose level 1, and 3 other interventions for Rheumatoid Arthritis. Completed, enrolled 41 participants across 8 sites in 3 countries.
Detailed Summary
This study will evaluate the safety and tolerability of PF-04236921 administered monthly as three intravenous infusions. Each group of patients will be assigned to a dose level; Safety and tolerability of a low dose level will be required before proceeding to successively higher dose levels. Blood tests will be performed to measure the amount of drug and changes in measures of inflammation.
Study Details
Timeline
Interventions
intravenous infusion on three consecutive months
intravenous infusion on three consecutive months
intravenous infusion on three consecutive months
intravenous infusion on three consecutive months
intravenous infusion on 3 consecutive months