At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A National, Prospective, Randomized, Multicenter, Controlled Head-to-Head Comparison of Bioactive Glass and Beta-Tricalcium Phosphate as Bone Graft Substitute in Filling of Contained Bone Defects
In Brief
An observational study evaluating Bioactive glass, Beta-tricalcium phosphate (ChronOs), and 2 other interventions for Bone Neoplasm. Completed, enrolled 120 participants across 5 sites.
Detailed Summary
This study is designed to perform a head-to-head comparison of two synthetic ceramic bone graft substitutes, bioactive glass (BAG) and beta-tricalcium phosphate (TCP), in filling of contained bone defects following surgical evacuation of benign bone tumor or tumor-like conditions. Based on the investigators' previous preclinical research and an ongoing single-center randomized clinical trial on bioactive glass filling, the investigators expect BAG filling to be more efficient compared to TCP in promotion of defect healing and functional recovery after surgery.
Study Details
Timeline
Interventions
Surgical implantation
Surgical implantation
Surgical transplantation from iliac crest
Surgical transplantation