CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 54 enrolled
Drug / intervention
Duac +1 moredrug
Likely dose
Duac: clindamycin and benzoyl peroxide topical gel once a day; Ziana: clindamycin and tretinoin gel once a dayAI-extracted
Key inclusion· 3
  • ✓Age at least 12 years
  • ✓Mild to moderate facial acne vulgaris
  • ✓Able to understand study requirements and provide informed consent
Key exclusion· 7
  • ✕Allergy or sensitivity to any component of the test medication
  • ✕Hypersensitivity to any component of investigational formulations
  • ✕History of enteritis, ulcerative colitis, pseudomembranous colitis, or antibiotic-associated colitis
  • ✕Presence of beards or sideburns

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00841776
NCT00841776Phase 4Completed
CompareCT.gov

Comparative Antimicrobial Efficacy of Two Topical Acne Therapies for the Treatment of Moderate to Moderately Severe Facial Acne Vulgaris

Stiefel, a GSK Company·interventional·Posted Feb 11, 2009·Updated May 25, 2017

In Brief

A Phase 4 clinical trial evaluating Duac and Ziana gel for Acne. Completed, enrolled 54 participants across 2 sites.

Detailed Summary

The purpose of the study is to determine the development of microbial resistance when using one of two topical acne therapies for the treatment of facial acne vulgaris.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsAcne
CountriesUnited States
CollaboratorsGlaxoSmithKline

Timeline

Phase 4CompletedFinished
20082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedFeb 11, 2009
Enrollment StartAug 1, 2007
Primary CompletionNov 1, 2008
Study CompletionJan 1, 2009
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 17.4 years ago

Interventions

Duacdrug

Clindamycon and benzoyl peroxide topical gel once a day for 12 weeks

Ziana geldrug

Clindamycin and tretinoin gel once a day for 12 weeks.