CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 101 enrolled
Drug / intervention
MRI +1 moreradiation
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00850538
NCT00850538N/ACompleted
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The Role of Bone and Its Measurement in Knee Osteoarthritis

The New England Baptist Hospital·observational·Posted Feb 25, 2009·Updated Dec 4, 2015

In Brief

An observational study evaluating MRI and Primary Total Knee Replacement for Osteoarthritis, Knee. Completed, enrolled 101 participants across 1 site.

Detailed Summary

The purpose of the study is to investigate protein and gene expression among damaged knee tissues. We will perform MRI's on subjects prior to total knee replacement to identify the location of bone marrow lesions. Connective tissues including tendon, ligament, and meniscus specimens normally discarded from total joint replacements will be used for live cell harvest, and protein and gene expression analyses of tissue or cultured cells.

Study Details

Study Typeobservational
Allocation--
Masking--
Primary Purpose--
ConditionsOsteoarthritis, Knee
CountriesAustralia
Collaborators--

Timeline

N/ACompletedFinished
20082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedFeb 25, 2009
Enrollment StartJul 1, 2008
Primary CompletionApr 1, 2013
TodayJul 2, 2026
Enrollment to primary: 4.8 yearsPosted 17.4 years ago

Interventions

MRIradiation

1.5T MRI exam of signal knee with knee coil (estimated time: 35 minutes)

Primary Total Knee Replacementprocedure

Fluid, bone, and meniscus specimens obtained from total joint replacement will be collected.