CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 795 enrolled
Drug / intervention
CP-690,550 +3 moredrug
Likely dose
CP-690,550 5 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00856544
NCT00856544Phase 3Completed
CompareCT.gov

Phase 3, Randomized, Double Blind, Placebo Controlled Study Of The Safety And Efficacy Of 2 Doses Of CP 690,550 In Patients With Active Rheumatoid Arthritis On Background DMARDS

Pfizer·interventional·Posted Mar 5, 2009·Updated Jan 10, 2013

In Brief

A Phase 3 clinical trial evaluating CP-690,550 and Placebo for Arthritis, Rheumatoid. Completed, enrolled 795 participants across 133 sites in 20 countries.

Detailed Summary

This Phase 3 study is intended to provide evidence that CP-690,550 dosed 5 mg BID and 10 mg BID is safe and effective when used in combination with a variety of traditional disease modifying antirheumatic drugs in adult patients with rheumatoid arthritis. It is intended to confirm the benefits of CP-690,550 in improving signs and symptoms and physical function that were observed in the Phase 2 rheumatoid arthritis studies.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsArthritis, Rheumatoid
CountriesAustralia, Chile, China, Colombia, Croatia, Denmark, Finland, Germany, Greece, Malaysia, Mexico, Poland, Russia, Slovakia, Spain, Sweden, Thailand, United Kingdom, United States, Venezuela
Collaborators--

Timeline

Phase 3CompletedFinished
200920102011201220132014201520162017201820192020202120222023202420252026
First PostedMar 5, 2009
Enrollment StartMay 1, 2009
Primary CompletionJan 1, 2011
TodayJul 2, 2026
Enrollment to primary: 1.7 yearsPosted 17.3 years ago

Interventions

CP-690,550drug

Film coated tablet, 5 mg PO BID, 1 year

CP-690,550drug

Film coated tablet, 10 mg PO BID, 1 year

Placebodrug

Film coated tablet, 1 tablet PO BID, 3-6 months

Placebodrug

Film coated tablet, 1 tablet PO BID, 3-6 months