At a glance
ClinicalIndex Comparison Record- ✓Children age 6 months through 17 years undergoing interventional neuroradiologic procedures under general anesthesia
- ✓ASA physical status I–III
- ✓No anesthetic procedure for more than 30 days prior to enrollment
- ✕Current digoxin therapy
- ✕Severe congestive heart failure or pulmonary hypertension requiring vasodilators
- ✕Hepatic or renal dysfunction
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Use of Dexmedetomidine for Emergence Delirium in Children Undergoing General Anesthesia for Endovascular Interventional Neuroradiologic Procedures
In Brief
A Phase 3 clinical trial evaluating Dexmedetomidine and Saline for Agitation and 2 related conditions. Completed, enrolled 33 participants across 1 site.
Detailed Summary
Emergence delirium (ED) from general anesthesia posts risk and harm to pediatric population undergo general anesthesia. The purpose of the study is to compare the use of dexmedetomidine versus placebo in reducing the incidence and severity of ED in a pediatric neurosurgical population.
Study Details
Timeline
Interventions
Dexmedetomidine will be dissolved in saline. An initial loading dose of 1.0 mg/kg given over 10 minutes followed by a continuous infusion at 0.4-0.7 mg/kg/hour. Beginning approximately one hour prior to end of surgery and continuing for one hour of recovery in the PACU and the PICU. This, the maximum dose for any one patient will be 2.4 mg/kg
Given by a continuous infusion