CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 105 enrolled
Drug / intervention
olmesartan medoxomil and a CCB +1 moredrug
Likely dose
Olmesartan medoxomil tablet plus either a CCB tablet or diuretic tablet, once daily for 8 weeksAI-extracted
Key inclusion· 2
  • ✓Mean seated blood pressure ≥140/90 mmHg while on olmesartan medoxomil monotherapy
  • ✓Mean 24-hour ambulatory blood pressure ≥135/80 mmHg while on olmesartan medoxomil monotherapy
Key exclusion· 2
  • ✕Secondary hypertension (hypertension from an identifiable secondary cause)
  • ✕Any serious disorder that may impair ability to evaluate drug efficacy or safety

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00858702
NCT00858702Phase 4Completed
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Add-on Study of CCBs or Diuretics in Essential Hypertension Not Achieving Target Blood Pressure on Olmesartan Medoxomil Alone

Daiichi Sankyo Co., Ltd.·interventional·Posted Mar 10, 2009·Updated Oct 11, 2017

In Brief

A Phase 4 clinical trial evaluating olmesartan medoxomil and a CCB and olmesartan medoxomil and a diuretic for Hypertension. Completed, enrolled 105 participants across 1 site.

Detailed Summary

The purpose of the study is to test the efficacy and safety of the combination of Calcium Channel Blockers (CCBs)(of the dihydropyridine class) or Diuretics (of the thiazide class) and olmesartan medoxomil in essential hypertensive patients whose blood pressure is not adequately controlled with olmesartan medoxomil alone

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHypertension
CountriesJapan
Collaborators--

Timeline

Phase 4CompletedFinished
20052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedMar 10, 2009
Enrollment StartFeb 1, 2005
Primary CompletionJul 1, 2005
Study CompletionNov 1, 2005
TodayJul 2, 2026
Enrollment to primary: 5 monthsPosted 17.3 years ago

Interventions

olmesartan medoxomil and a CCBdrug

olmesartan medoxomil tablets and a CCB tablet once daily for 8 weeks

olmesartan medoxomil and a diureticdrug

olmesartan medoxomil tablets and a diuretic tablet, once daily for 8 weeks