CI

At a glance

ClinicalIndex Comparison Record
Phase 4Completed· 156 enrolled
Drug / intervention
Saline +2 moredrug
Likely dose
Saline 3.3 mLfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00864682
NCT00864682Phase 4Completed
CompareCT.gov

Propofol Mixed With Lidocaine Versus Lidocaine Pretreatment With Tourniquet for Alleviation of Pain Associated With Propofol Injection

Benaroya Research Institute·interventional·Posted Mar 19, 2009·Updated Jan 27, 2021

In Brief

A Phase 4 clinical trial evaluating Saline, Lidocaine / propofol admixture, and 1 other intervention for Pain. Completed, enrolled 156 participants across 1 site.

Detailed Summary

Injection of propofol is associated with discomfort in subsets of patients. Local anesthetics have been shown to attenuate this response in some patients. This randomized, double-blind, placebo-controlled trial tests the hypothesis that lidocaine mixed with propofol will be superior to lidocaine administered directly into the vein, under tourniquet control, prior to injection of propofol. Both groups are expected to be superior to placebo.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPain
CountriesUnited States
Collaborators--

Timeline

Phase 4CompletedFinished
20082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedMar 19, 2009
Enrollment StartJan 1, 2008
Primary CompletionMar 1, 2009
Study CompletionApr 1, 2009
TodayJul 2, 2026
Enrollment to primary: 1.2 yearsPosted 17.3 years ago

Interventions

Salinedrug

3.3 mL normal saline

Lidocaine / propofol admixturedrug

lidocaine 50 mg plus propofol 50 mg intravenous (iv)

lidocaine pretreatmentdrug

lidocaine 50 mg iv under tourniquet-control