CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 22 enrolled
Drug / intervention
Chlorine dioxide and scraper +1 moredrug
Likely dose
Chlorine dioxide and scraper 20mlfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00867035
NCT00867035N/ACompleted
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Bad Breath Response to Tongue Scraper and Rinses, a Double-blind, Randomized, Parallel Group Clinical Trial.

University of California, San Francisco·interventional·Posted Mar 23, 2009·Updated May 16, 2013

In Brief

A clinical study evaluating Chlorine dioxide and scraper and Chlorhexidine gluconate and scraper for Halitosis. Completed, enrolled 22 participants across 1 site.

Detailed Summary

Medical center personnel were screened organoleptically for bad breath by 2 investigators using Rosenberg scale 0-5, and measurement of breath sample in portable gas chromatograph. With a threshold score of 2 or more, or 75parts per billion(ppb) hydrogen sulfide(H2S), subjects invited to enter clinical trial of the mechanical effect of daily tongue scraping with the adjunctive use of 0.12% chlorhexidine gluconate mouthwash or 0.1% stabilized chlorine dioxide mouthwash. Subjects randomly assigned in double-blind trial for one week. The null hypothesis is there will be no difference between the two rinses as adjuncts to tongue scraping.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsHalitosis
CountriesUnited States
Collaborators--

Timeline

N/ACompletedFinished
20082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedMar 23, 2009
Enrollment StartMar 1, 2008
Primary CompletionMar 1, 2009
Study CompletionJun 1, 2009
TodayJul 2, 2026
Enrollment to primary: 1 yearPosted 17.3 years ago

Interventions

Chlorine dioxide and scraperdrug

20ml of mouthwash used for 30sec as adjunct to tongue scraper twice a day

Chlorhexidine gluconate and scraperdrug

The intervention was accomplished by subject after instructions by investigator: twice a day the scraper was used for 4 strokes then 20ml 0.12% chlorhexidine gluconate rinse for 30sec, for one week.