At a glance
ClinicalIndex Comparison RecordStandardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
Low Glycemic Index Dietary Intervention Program in Nonalcoholic Fatty Liver Disease - A Randomized Controlled Trial
In Brief
A clinical study evaluating Low glycemic index dietary intervention program and simple lifestyle advice for Nonalcoholic Fatty Liver Disease. Completed, enrolled 159 participants across 1 site.
Detailed Summary
Nonalcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in affluent countries. It may progress to cirrhosis and liver cancer. At present, there is no approved drug for NAFLD. Although healthy diet and exercise is often recommended, there is little supportive evidence. Therefore, the investigators plan to conduct a randomized controlled trial comparing a low glycemic index dietary intervention program and simple lifestyle advice in NAFLD patients. The primary endpoint is resolution of NAFLD. Non-invasive tests will be used to assess the study subjects. Proton-magnetic resonance spectroscopy is used to quantify hepatic triglyceride content, and transient elastography is used to quantify liver fibrosis.
Study Details
Timeline
Interventions
The intervention group involves dietary advice and monitoring. No drug or invasive procedure is involved.
The control group receives lifestyle advice from a clinician, and the clinical care is not inferior to current practice.