At a glance

ClinicalIndex Comparison Record

Phase 3Completed· 123 enrolled

Drug / intervention

Adapalene BPO Gel standard daily overnight application +3 moredrug

Likely dose

Not stated in record

Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00883233

NCT00883233Phase 3Completed

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Efficacy and Safety Comparison of Four Different Regimens of Adapalene 0.1% / Benzoyl Peroxide 2.5% Gel in the Treatment of Acne Vulgaris

Galderma R&D·interventional·Posted Apr 17, 2009·Updated Feb 18, 2021

In Brief

A Phase 3 clinical trial evaluating Adapalene BPO Gel standard daily overnight application, Adapalene-BPO 3-hour daily application before bedtime, and 2 other interventions for Acne. Completed, enrolled 123 participants across 2 sites.

Detailed Summary

The purpose of this study is to compare the tolerability of 3 treatment regimens containing Adapalene 0.1% / Benzoyl Peroxide 2.5% Gel with that of Adapalene 0.1% /Benzoyl Peroxide 2.5% Gel standard daily overnight application for 12 weeks in the treatment of acne vulgaris. The efficacy of the four treatment regimens will also be evaluated.

Study Details

Study Typeinterventional

Allocation--

Masking--

Primary Purpose--

ConditionsAcne

CountriesCanada

Collaborators--

Timeline

Phase 3CompletedFinished

200920102011201220132014201520162017201820192020202120222023202420252026

Enrollment StartApr 2009

First PostedApr 2009

Primary CompletionSep 2009

TodayJul 2026

First PostedApr 17, 2009

Enrollment StartApr 1, 2009

Primary CompletionSep 1, 2009

TodayJul 2, 2026

Enrollment to primary: 5 monthsPosted 17.2 years ago

Interventions

Adapalene BPO Gel standard daily overnight applicationdrug

Adapalene 0.1% /Benzoyl Peroxide 2.5% Gel standard daily overnight application for 12 week

Adapalene-BPO 3-hour daily application before bedtimedrug

Adapalene 0.1% / Benzoyl Peroxide 2.5% Gel 3-hour daily application before bedtime for first 4 weeks and then standard overnight daily application for the following 8 weeks

Adapalene-BPO Gel every other day applicationdrug

Adapalene 0.1% /Benzoyl Peroxide 2.5% Gel every other day application for the first 4 weeks and then standard overnight daily application for the following 8 weeks

Adapalene-BPO Gel standard+Cetaphil® Moisturizing Lotiondrug

Adapalene 0.1% / Benzoyl Peroxide 2.5% Gel standard daily overnight application with Cetaphil® Moisturizing Lotion application at wake-up time for the first 4 weeks and then standard daily overnight application for the following 8 weeks