CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 1,088 enrolled
Drug / intervention
Abiraterone acetate +2 moredrug
Likely dose
Abiraterone acetate 1000 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00887198
NCT00887198Phase 3Completed

A Phase 3, Randomized, Double-blind, Placebo-Controlled Study of Abiraterone Acetate (CB7630) Plus Prednisone in Asymptomatic or Mildly Symptomatic Patients With Metastatic Castration-Resistant Prostate Cancer

Janssen Research & Development, LLC·interventional·Posted Apr 23, 2009·Updated Feb 4, 2025

In Brief

A Phase 3 clinical trial evaluating Abiraterone acetate, Placebo, and 1 other intervention for Prostate Cancer. Completed, enrolled 1,088 participants across 134 sites in 11 countries.

Detailed Summary

This is a phase 3 study to compare the clinical benefit of abiraterone acetate plus prednisone with placebo plus prednisone in asymptomatic or mildly symptomatic patients with metastatic castration-resistant prostate cancer (CRPC).

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsProstate Cancer
CountriesAustralia, Belgium, Canada, France, Germany, Greece, Netherlands, Spain, Sweden, United Kingdom, United States
Collaborators--

Timeline

Phase 3CompletedFinished
200920102011201220132014201520162017201820192020202120222023202420252026
First PostedApr 23, 2009
Enrollment StartApr 28, 2009
Primary CompletionMar 31, 2014
Study CompletionMay 25, 2017
TodayJul 2, 2026
Enrollment to primary: 4.9 yearsPosted 17.2 years ago

Interventions

Abiraterone acetatedrug

1000 mg per day (4 x 250-mg tablets) taken orally.

Placebodrug

4 placebo tablets per day taken orally.

Prednisonedrug

5 mg tablet orally twice daily.