CI

At a glance

ClinicalIndex Comparison Record
Phase 3Completed· 561 enrolled
Drug / intervention
Aclidinium bromide +2 moredrug
Likely dose
Aclidinium bromide 200 μgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00891462
NCT00891462Phase 3Completed

Efficacy and Safety of Aclidinium Bromide at Two Dose Levels (200 μg Twice Daily, 400 μg Twice Daily) vs. Placebo When Administered to Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD)

AstraZeneca·interventional·Posted May 1, 2009·Updated Jan 6, 2017

In Brief

A Phase 3 clinical trial evaluating Aclidinium bromide and Placebo for Chronic Obstructive Pulmonary Disease. Completed, enrolled 561 participants across 112 sites in 2 countries.

Detailed Summary

The purpose of this study is to assess the efficacy (effectiveness) and safety of aclidinium bromide doses as compared to placebo in the treatment of moderate to severe chronic obstructive pulmonary disease. The study will be 16 weeks in duration; 2-week run-in period, 12-week double-blind treatment, and 2-week follow-up phone visit.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesCanada, United States
Collaborators--

Timeline

Phase 3CompletedFinished
200920102011201220132014201520162017201820192020202120222023202420252026
First PostedMay 1, 2009
Enrollment StartApr 1, 2009
Primary CompletionNov 1, 2009
TodayJul 2, 2026
Enrollment to primary: 7 monthsPosted 17.2 years ago

Interventions

Aclidinium bromidedrug

Aclidinium bromide 200 μg, oral inhalation twice per day for 12 weeks of treatment

Aclidinium bromidedrug

Aclidinium bromide 400 μg, oral inhalation twice per day for 12 weeks of treatment

Placebodrug

Dose-matched placebo, oral inhalation twice per day for 12 weeks of treatment