CI

At a glance

ClinicalIndex Comparison Record
Phase 2Completed· 314 enrolled
Drug / intervention
Pre-intubation CHX +1 moreprocedure
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00893763
NCT00893763Phase 2Completed
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Oral Care Intervention in Mechanically Ventilated Adults

University of South Florida·interventional·Posted May 6, 2009·Updated Jan 11, 2016

In Brief

A Phase 2 clinical trial evaluating Pre-intubation CHX and Control for Infections, Hospital and 2 related conditions. Completed, enrolled 314 participants across 1 site.

Detailed Summary

Ventilator-associated pneumonia (VAP) is a serious complication in mechanically ventilated critically ill patients. The intervention tested in this project (swabbing the mouth with chlorhexidine before the endotracheal tube is inserted) could reduce the risk of ventilator-associated pneumonia.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsInfections, Hospital, Ventilator-Associated Pneumonia, Mechanical Ventilation Complication
CountriesUnited States
CollaboratorsNational Institute of Nursing Research (NINR)

Timeline

Phase 2CompletedFinished
200920102011201220132014201520162017201820192020202120222023202420252026
First PostedMay 6, 2009
Enrollment StartSep 1, 2008
Primary CompletionJun 1, 2012
TodayJul 2, 2026
Enrollment to primary: 3.8 yearsPosted 17.2 years ago

Interventions

Pre-intubation CHXprocedure

Oral application of 5 ml CHX gluconate 0.12% solution pre-intubation, and 5 ml CHX gluconate 0.12% solution twice a day following intubation.

Controlprocedure

No pre-intubation intervention, 5 ml CHX gluconate 0.12% solution twice a day following intubation