CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 23 enrolled
Drug / intervention
AutoVPAP +1 moredevice
Likely dose
Not stated in record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00901485
NCT00901485N/ACompleted
CompareCT.gov

Autotitrating Non-invasive Ventilation (NIV) Versus Standard NIV; a Randomised Crossover Trial in Patients With Newly Diagnosed Hypoventilation

ResMed·interventional·Posted May 13, 2009·Updated Jun 18, 2021

In Brief

A clinical study evaluating AutoVPAP and VPAPIIIST-A for Nocturnal Hypoventilation and 2 related conditions. Completed, enrolled 23 participants across 1 site.

Detailed Summary

The aim of the study is to compare the efficacy and tolerance of autotitrating non-invasive ventilation (NIV) versus standard NIV in patients with newly diagnosed nocturnal hypoventilation who have never experienced nocturnal, home NIV.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsNocturnal Hypoventilation, Neuromuscular Disease, Chest Wall Disorder
CountriesUnited Kingdom
CollaboratorsRoyal Brompton & Harefield NHS Foundation Trust

Timeline

N/ACompletedFinished
200920102011201220132014201520162017201820192020202120222023202420252026
First PostedMay 13, 2009
Enrollment StartApr 1, 2009
Primary CompletionMar 1, 2011
TodayJul 2, 2026
Enrollment to primary: 1.9 yearsPosted 17.1 years ago

Interventions

AutoVPAPdevice

Automatically titrated non-invasive ventilator, with target gross alveolar ventilation and back up respiratory rate determined by learn function. Nocturnal use for one month in patient's home.

VPAPIIIST-Adevice

Standard non-invasive ventilator with pressure and respiratory rate settings determined by healthcare professional. Nocturnal use for one month in the patient's home.