CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 22 enrolled
Drug / intervention
Vitamin D3 +1 moredrug
Likely dose
Vitamin D3 4000IUfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00903344
NCT00903344N/ACompleted

Impact of Vitamin D Supplementation on Lactation Associated Bone Loss

Leigh Eck, MD·interventional·Posted May 18, 2009·Updated Aug 18, 2014

In Brief

A clinical study evaluating Vitamin D3 and Multivitamin for Osteoporosis. Completed, enrolled 22 participants across 1 site.

Detailed Summary

Studies have shown that lactation is associated with a loss of bone density from four to seven percent at the spine and hip among women who lactate for six months. Decline in bone density with lactation occurs rapidly. Although bone density increases after weaning, there is controversy on whether or not it is completely restored. Epidemiological studies find no significant negative impact of lactation on bone mass or fractures, and in fact there is evidence that lactation has a positive effect on bone mass. We think that interventions that attenuate this physiologic loss of bone that is associated with lactation and accelerate restoration of bone mass after weaning may result in improved long term bone mass and diminished fracture risk.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsOsteoporosis
CountriesUnited States

Timeline

N/ACompletedFinished
200920102011201220132014201520162017201820192020202120222023202420252026
First PostedMay 18, 2009
Enrollment StartDec 1, 2009
Primary CompletionJun 1, 2012
TodayJul 2, 2026
Enrollment to primary: 2.5 yearsPosted 17.1 years ago

Interventions

Vitamin D3drug

4000IU vitamin D3 tablet taken daily

Multivitamindietary

Multivitamin containing 400IU vitamin D in tablet taken daily