CI

At a glance

ClinicalIndex Comparison Record
Phase 1Completed· 9 enrolled
Drug / intervention
dexamethasone +2 moredrug
Likely dose
dexamethasone 4 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00906503
NCT00906503Phase 1Completed
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Does Ultra Short-term Steroid Therapy Increase the Accuracy of FDG-PET/CT in Evaluation of Pulmonary Nodules?

Barbara Ann Karmanos Cancer Institute·interventional·Posted May 21, 2009·Updated Apr 7, 2015

In Brief

A Phase 1 clinical trial evaluating dexamethasone, PET/Computed Tomography (CT), and 1 other intervention for Pulmonary Nodule. Completed, enrolled 9 participants across 2 sites.

Detailed Summary

RATIONALE: Imaging procedures, such as fludeoxyglucose F 18 (FDG)-PET/CT scan, done before and after steroid therapy may help doctors assess a patient's response to treatment and help plan the best treatment. PURPOSE: This phase I trial is studying fludeoxyglucose F 18 PET scan performed before and after ultra short-term dexamethasone therapy to see how well it measures changes in nodules in patients with lung nodules.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPulmonary Nodule
CountriesUnited States
CollaboratorsNational Cancer Institute (NCI)

Timeline

Phase 1CompletedFinished
200920102011201220132014201520162017201820192020202120222023202420252026
First PostedMay 21, 2009
Enrollment StartApr 1, 2009
Primary CompletionFeb 1, 2011
Study CompletionApr 1, 2012
TodayJul 2, 2026
Enrollment to primary: 1.8 yearsPosted 17.1 years ago

Interventions

dexamethasonedrug

Four 4 mg dexamethasone tablets by mouth after food 40, 28, 16 and 4 hrs before the scan

PET/Computed Tomography (CT)procedure

Radioactive tracer (18F-FDG), approx. 1 ml (1/5 of a tsp.); Scanned for about 15 minutes for imaging the lungs

fludeoxyglucose (18F)radiation

Radioactive tracer (18F-FDG), approx. 1 ml (1/5 of a tsp.); Scanned for about 15 minutes for imaging the lungs