CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 109 enrolled
Drug / intervention
12 mg Lutein + Zeaxanthin +1 moredietary
Likely dose
12 mg Lutein + Zeaxanthinfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00909090
NCT00909090N/ACompleted

Effects of Lutein and Zeaxanthin Upon MPOD and Its Effects Upon Glare Disability, Photostress Recovery, and Contrast Enhancement in Healthy Subjects: A Randomized, Double-blind Placebo-controlled Study

University of Georgia·interventional·Posted May 27, 2009·Updated Jul 13, 2020

In Brief

A clinical study evaluating 12 mg Lutein + Zeaxanthin and Visually identical placebo for Vision, Entoptic. Completed, enrolled 109 participants across 1 site.

Detailed Summary

The purpose of this study is: I. To measure MP optical density (MPOD) in two groups (experimental and placebo) of 50 subjects each (N = 100), during an Lutein + Zeaxanthin supplementation period of 12 months. II. To test the hypothesis that increases in MP (via 12 mg daily Lutein + Zeaxanthin supplementation) will result in significantly improved visual performance under disability glare conditions. III. To test the hypothesis that increases in MP (via 12 mg daily L + Z supplementation) will result in significantly reduced photostress recovery times. IV. To test the hypothesis that increases in MP (via 12 mg daily L + Z supplementation) will result in improved contrast enhancement.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
CountriesUnited States

Timeline

N/ACompletedFinished
200920102011201220132014201520162017201820192020202120222023202420252026
First PostedMay 27, 2009
Enrollment StartMay 1, 2009
Primary CompletionDec 1, 2012
TodayJul 2, 2026
Enrollment to primary: 3.6 yearsPosted 17.1 years ago

Interventions

12 mg Lutein + Zeaxanthindietary

10 mg FloraGlo lutein + 2 mg Optisharp zeaxanthin, taken once daily for one year

Visually identical placebodietary

Visually identical placebo, taken once daily for one year