At a glance
ClinicalIndex Comparison RecordPhase 3Completed· 238 enrolled
Drug / intervention
Tramadol OAD +3 moredrug
Likely dose
Tramadol OAD 100mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.
Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.
A Comparison of the Analgesic Efficacy and Safety of Once Daily Tramadol OAD Tablets to Twice Daily Tramadol BID for the Treatment of Osteoarthritis of the Knee (Extension Protocol) and Open Label Safety Follow-Up
In Brief
A Phase 3 clinical trial evaluating Tramadol OAD and Tramadol OAD 100mg for Pain and Osteoarthritis, Knee. Completed, enrolled 238 participants.
Detailed Summary
The purpose of this study is to evaluate the long-term safety (up to one year) of Tramadol Once-A-Day (OAD) tablets at the highest doses: 200-400 mg
Study Details
Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsPain, Osteoarthritis, Knee
Countries--
Collaborators--
Timeline
Phase 3CompletedFinished
20022003200420052006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
Enrollment StartMar 2002
Primary CompletionJul 2003
First PostedJun 2009
TodayJul 2026
First PostedJun 3, 2009
Enrollment StartMar 1, 2002
Primary CompletionJul 1, 2003
TodayJul 2, 2026
Enrollment to primary: 1.3 yearsPosted 17.1 years ago
Interventions
Tramadol OADdrug
Tramadol OADdrug
Tramadol OADdrug
Tramadol OAD 100mgdrug