CI

At a glance

ClinicalIndex Comparison Record
N/ACompleted· 23 enrolled
Drug / intervention
Donepezil +1 moredrug
Likely dose
Donepezil 5 mgfrom record
Structured eligibility isn't available for this trial yet — see the full criteria in the Eligibility tab below.

Standardized by ClinicalIndex from the ClinicalTrials.gov record · verify against the source.

Search/NCT00912808
NCT00912808N/ACompleted
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A Study of Cholinergic Augmentation in Frequently Falling Subjects With Parkinson's

Oregon Health and Science University·interventional·Posted Jun 3, 2009·Updated May 8, 2018

In Brief

A clinical study evaluating Donepezil and Sugar Pill (placebo) for Parkinson's Disease. Completed, enrolled 23 participants.

Detailed Summary

The purpose of this study is to find out if a medication that increases levels of a brain chemical called acetylcholine will improve balance and reduce falls in patients with parkinson's disease who have the problem of very poor balance and are frequently falling or nearly falling on a daily basis. Donepezil, a drug approved for the treatment of Alzheimer's dementia, will reduce falls in subjects with Parkinson's disease and balance impairment.

Study Details

Study Typeinterventional
Allocation--
Masking--
Primary Purpose--
ConditionsParkinson's Disease
Countries--
Collaborators--

Timeline

N/ACompletedFinished
2006200720082009201020112012201320142015201620172018201920202021202220232024202520262027
First PostedJun 3, 2009
Enrollment StartOct 1, 2005
Primary CompletionFeb 1, 2009
TodayJul 2, 2026
Enrollment to primary: 3.3 yearsPosted 17.1 years ago

Interventions

Donepezildrug

donepezil, 5 mg, capsule, once a day, 3 weeks

Sugar Pill (placebo)drug

sugar pill, one capsule, once a day, 3 weeks